A 70-year-old man is started on gentamicin IV for suspected Gram-negative sepsis. He has baseline chronic kidney disease with an eGFR of 45 mL/min/1.7...

Question

A 70-year-old man is started on gentamicin IV for suspected Gram-negative sepsis. He has baseline chronic kidney disease with an eGFR of 45 mL/min/1.73m². According to BNF guidance regarding aminoglycoside prescribing, what is essential?

Accepted Answer

Administer subsequent doses based on pre-dose (trough) levels

Answer

Administer a smaller loading dose

Answer

Administer subsequent doses based on post-dose (peak) levels

Answer

Measure serum levels only after 72 hours

Answer

Avoid concomitant administration of IV fluids

ukmla MCQ (SBA): Gentamicin monitoring

A 70-year-old man is started on gentamicin IV for suspected Gram-negative sepsis. He has baseline chronic kidney disease with an eGFR of 45 mL/min/1.73m². According to BNF guidance regarding aminoglycoside prescribing, what is essential?