Practice question

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A 68-year-old man with a history of ischaemic heart disease and chronic kidney disease (eGFR 40 ml/min/1.73m²) requires anticoagulation for newly diagnosed atrial fibrillation (CHA₂DS₂-VASc score 4). According to NICE NG196, which anticoagulant is generally preferred, assuming no other contraindications?

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