A 50-year-old woman with rheumatoid arthritis, managed with Methotrexate 15mg weekly and Folic Acid 5mg weekly (on a different day), presents with pai...

Question

A 50-year-old woman with rheumatoid arthritis, managed with Methotrexate 15mg weekly and Folic Acid 5mg weekly (on a different day), presents with painful oral ulcers and nausea persisting for 3 days. Blood tests reveal: Hb 110 g/L, WBC 2.5 x10$^9$/L, Neutrophils 0.8 x10$^9$/L, Platelets 95 x10$^9$/L. What is the most likely cause of these findings?

Accepted Answer

Methotrexate toxicity

Answer

Disease flare of rheumatoid arthritis

Answer

Folic acid deficiency

Answer

Intercurrent viral infection

Answer

Sjogren's syndrome

mrcp part 1 MCQ (SBA): Methotrexate Toxicity