A 68-year-old woman presents with bone pain in her spine and hypercalcaemia. Blood tests reveal a raised total protein and rouleaux formation on the b...

Question

A 68-year-old woman presents with bone pain in her spine and hypercalcaemia. Blood tests reveal a raised total protein and rouleaux formation on the blood film. Serum protein electrophoresis shows a monoclonal spike. Which additional investigation is essential to confirm the diagnosis?

Accepted Answer

Bone marrow biopsy

Answer

Skeletal survey X-ray

Answer

CT spine

Answer

Serum free light chains

Answer

CRP measurement

ukmla MCQ (SBA): Multiple Myeloma

A 68-year-old woman presents with bone pain in her spine and hypercalcaemia. Blood tests reveal a raised total protein and rouleaux formation on the blood film. Serum protein electrophoresis shows a monoclonal spike. Which additional investigation is essential to confirm the diagnosis?