Question

A 35-year-old woman presents with right lower quadrant abdominal pain, diarrhoea, and weight loss. Colonoscopy shows segmental, transmural inflammation with skip lesions. Which feature best differentiates Crohn's disease from ulcerative colitis?

Accepted Answer

Granulomas on biopsy

Answer

Bloody diarrhoea

Answer

Continuous colonic involvement

Answer

Inflammation limited to the mucosa

Answer

Association with primary sclerosing cholangitis

Practice question

A 35-year-old woman presents with right lower quadrant abdominal pain, diarrhoea, and weight loss. Colonoscopy shows segmental, transmural inflammation with skip lesions. Which feature best differentiates Crohn's disease from ulcerative colitis?