A 65-year-old is taking warfarin for atrial fibrillation and wishes to start over-the-counter St John's Wort for mild depression. According to the BNF...

Question

A 65-year-old is taking warfarin for atrial fibrillation and wishes to start over-the-counter St John's Wort for mild depression. According to the BNF, which interaction is most likely?

Accepted Answer

Decreased anticoagulant effect, leading to thrombosis

Answer

Increased anticoagulant effect, leading to bleeding

Answer

No significant interaction

Answer

Risk of serotonin syndrome

Answer

Hypotension

MCQ (SBA): Pharmacology & Prescribing

A 65-year-old is taking warfarin for atrial fibrillation and wishes to start over-the-counter St John's Wort for mild depression. According to the BNF, which interaction is most likely?