Question

A 60-year-old man with acromegaly has elevated IGF-1 and a pituitary adenoma on MRI. After transsphenoidal surgery, his IGF-1 remains high. According to NICE, which medication class is recommended next to control GH secretion?

Accepted Answer

Somatostatin analogues (e.g., octreotide)

Answer

Bromocriptine

Answer

Cabergoline

Answer

GH receptor antagonist (e.g., pegvisomant)

Answer

Glucocorticoid therapy

Practice question

A 60-year-old man with acromegaly has elevated IGF-1 and a pituitary adenoma on MRI. After transsphenoidal surgery, his IGF-1 remains high. According to NICE, which medication class is recommended next to control GH secretion?