A 60-year-old with Parkinson's disease has bothersome 'off' episodes and motor fluctuations on levodopa. According to NICE, which medication class may...

Question

A 60-year-old with Parkinson's disease has bothersome 'off' episodes and motor fluctuations on levodopa. According to NICE, which medication class may help reduce these fluctuations?

Accepted Answer

COMT inhibitors (e.g. entacapone)

Answer

Anticholinergics (e.g. trihexyphenidyl)

Answer

MAO-B inhibitors (e.g. selegiline) alone

Answer

Amantadine monotherapy

Answer

Beta-blockers

ukmla MCQ (SBA): Parkinson's disease

A 60-year-old with Parkinson's disease has bothersome 'off' episodes and motor fluctuations on levodopa. According to NICE, which medication class may help reduce these fluctuations?