Question

A 40-year-old woman presents with weight gain, easy bruising, and purple abdominal striae. A low-dose dexamethasone suppression test shows no cortisol suppression. According to NICE guidelines, which next test is crucial to localise the cause of Cushing's syndrome?

Accepted Answer

Plasma ACTH level measurement

Answer

High-dose dexamethasone suppression test

Answer

MRI of the pituitary gland

Answer

Abdominal CT for the adrenals

Answer

Inferior petrosal sinus sampling

Practice question

A 40-year-old woman presents with weight gain, easy bruising, and purple abdominal striae. A low-dose dexamethasone suppression test shows no cortisol suppression. According to NICE guidelines, which next test is crucial to localise the cause of Cushing's syndrome?