Question

A 24-year-old man with Crohn's disease presents with 3 weeks of worsening abdominal pain and diarrhoea. He has been on budesonide for mild disease. His inflammatory markers are high, and colonoscopy shows moderate-to-severe disease activity. What is the next recommended step?

Accepted Answer

Escalate to a conventional steroid (e.g., prednisolone) or consider biologics

Answer

Continue budesonide without change

Answer

Switch to 5-ASA (mesalazine) therapy

Answer

Immediate surgical resection

Answer

Probiotic therapy

Practice question

A 24-year-old man with Crohn's disease presents with 3 weeks of worsening abdominal pain and diarrhoea. He has been on budesonide for mild disease. His inflammatory markers are high, and colonoscopy shows moderate-to-severe disease activity. What is the next recommended step?