A 22-year-old presents with a painless rubbery lymph node in the neck, night sweats, and weight loss. Lymph node biopsy confirms Hodgkin lymphoma. Whi...

Question

A 22-year-old presents with a painless rubbery lymph node in the neck, night sweats, and weight loss. Lymph node biopsy confirms Hodgkin lymphoma. Which finding on biopsy is pathognomonic?

Accepted Answer

Reed-Sternberg cells

Answer

Philadelphia chromosome

Answer

Auer rods

Answer

Smudge cells

Answer

Bence Jones proteins

NICE Guideline NG52 on Hodgkin lymphoma MCQ (SBA): Hodgkin lymphoma

A 22-year-old presents with a painless rubbery lymph node in the neck, night sweats, and weight loss. Lymph node biopsy confirms Hodgkin lymphoma. Which finding on biopsy is pathognomonic?