Question

A 40-year-old woman presents with symmetrical joint pain and morning stiffness lasting more than 1 hour, improved by activity. Rheumatoid arthritis is suspected. According to NICE, which investigation is most specific for RA?

Accepted Answer

Anti-cyclic citrullinated peptide (anti-CCP) antibody

Answer

Rheumatoid factor

Answer

Erythrocyte sedimentation rate (ESR)

Answer

C-reactive protein (CRP)

Answer

X-ray of the hands

Practice question

A 40-year-old woman presents with symmetrical joint pain and morning stiffness lasting more than 1 hour, improved by activity. Rheumatoid arthritis is suspected. According to NICE, which investigation is most specific for RA?