Question

A 45-year-old woman with type 2 diabetes is prescribed metformin. She develops severe gastro-intestinal side effects. According to NICE, what is an alternative initial therapy if metformin is not tolerated?

Accepted Answer

Sulfonylurea (e.g. gliclazide)

Answer

Insulin therapy

Answer

GLP-1 agonist (e.g. exenatide)

Answer

DPP-4 inhibitor (e.g. sitagliptin)

Answer

SGLT2 inhibitor (e.g. canagliflozin)

Practice question

A 45-year-old woman with type 2 diabetes is prescribed metformin. She develops severe gastro-intestinal side effects. According to NICE, what is an alternative initial therapy if metformin is not tolerated?