Question

A 44-year-old man with generalized tonic-clonic seizures is prescribed phenytoin. According to the BNF, which pharmacokinetic property is unique to phenytoin?

Accepted Answer

Zero-order (saturable) kinetics at therapeutic doses

Answer

Linear kinetics at all concentrations

Answer

Complete renal excretion unchanged

Answer

Very short half-life

Answer

No protein binding

Practice question

A 44-year-old man with generalized tonic-clonic seizures is prescribed phenytoin. According to the BNF, which pharmacokinetic property is unique to phenytoin?