Question

A 70-year-old man with newly diagnosed multiple myeloma presents with bone pain, anemia, and renal impairment. According to NICE guidelines, which initial therapy is recommended for transplant-ineligible patients?

Accepted Answer

Melphalan, prednisolone, and thalidomide (MPT) or bortezomib-based regimens

Answer

High-dose chemotherapy with autologous stem cell transplant

Answer

Radiotherapy to all painful lesions

Answer

Imatinib therapy

Answer

Watchful waiting

Practice question

A 70-year-old man with newly diagnosed multiple myeloma presents with bone pain, anemia, and renal impairment. According to NICE guidelines, which initial therapy is recommended for transplant-ineligible patients?