A 27-year-old man presents with a 2-month history of low mood, anhedonia, and poor concentration. According to NICE guidelines, what is the first-line...

Question

A 27-year-old man presents with a 2-month history of low mood, anhedonia, and poor concentration. According to NICE guidelines, what is the first-line pharmacological treatment for moderate depression in an adult with no other comorbidities?

Accepted Answer

Selective serotonin reuptake inhibitor (SSRI, e.g., sertraline)

Answer

Tricyclic antidepressant (e.g., amitriptyline)

Answer

Serotonin-noradrenaline reuptake inhibitor (e.g., venlafaxine)

Answer

Monoamine oxidase inhibitor (e.g., phenelzine)

Answer

Antipsychotic medication

NICE Depression in adults guideline (NG222) MCQ (SBA): Depression

A 27-year-old man presents with a 2-month history of low mood, anhedonia, and poor concentration. According to NICE guidelines, what is the first-line pharmacological treatment for moderate depression in an adult with no other comorbidities?