Question

A 56-year-old patient with long-standing gastroesophageal reflux disease is found to have Barrett's oesophagus on endoscopy. Which factor is most significantly associated with increased risk of progression to oesophageal adenocarcinoma?

Accepted Answer

Presence of intestinal metaplasia with dysplasia

Answer

Short segment (<3cm) Barrett's oesophagus

Answer

Regular surveillance endoscopy

Answer

Eradication of H. pylori

Answer

Concurrent hiatal hernia

Practice question

A 56-year-old patient with long-standing gastroesophageal reflux disease is found to have Barrett's oesophagus on endoscopy. Which factor is most significantly associated with increased risk of progression to oesophageal adenocarcinoma?