Question

A 68-year-old heavy smoker with chronic cough, haemoptysis, and weight loss is found to have a suspicious mass on chest X-ray. Biopsy confirms squamous cell carcinoma of the lung. Which paraneoplastic syndrome is most commonly associated with squamous cell carcinoma of the lung?

Accepted Answer

Hypercalcaemia (due to PTHrP production)

Answer

SIADH (Syndrome of Inappropriate ADH secretion)

Answer

Cushing's syndrome (due to ectopic ACTH)

Answer

Lambert-Eaton myasthenic syndrome

Answer

Polycythaemia (due to erythropoietin production)

Practice question

A 68-year-old heavy smoker with chronic cough, haemoptysis, and weight loss is found to have a suspicious mass on chest X-ray. Biopsy confirms squamous cell carcinoma of the lung. Which paraneoplastic syndrome is most commonly associated with squamous cell carcinoma of the lung?