Question

A 40-year-old man with major depression has partial response to sertraline after 8 weeks. He has persistent moderate symptoms. According to NICE guidelines, what is the next best step?

Accepted Answer

Augment with another agent or switch to a different antidepressant

Answer

Stop sertraline and switch to a TCA immediately

Answer

Add a second SSRI

Answer

Start a mood stabiliser

Answer

Electroconvulsive therapy (ECT)

Practice question

A 40-year-old man with major depression has partial response to sertraline after 8 weeks. He has persistent moderate symptoms. According to NICE guidelines, what is the next best step?