Question

A 30-year-old patient with suspected Cushing's syndrome has elevated late-night salivary cortisol and clinical features of hypercortisolism. Which test is recommended next to confirm endogenous cortisol overproduction?

Accepted Answer

Low-dose dexamethasone suppression test

Answer

MRI pituitary scan

Answer

Plasma ACTH measurement

Answer

24-hour urinary free cortisol test

Answer

High-dose dexamethasone suppression test

Practice question

A 30-year-old patient with suspected Cushing's syndrome has elevated late-night salivary cortisol and clinical features of hypercortisolism. Which test is recommended next to confirm endogenous cortisol overproduction?