Question

A 60-year-old male with polycythaemia vera has itching after hot baths, headaches, and elevated haematocrit with a JAK2 mutation. Which first-line treatment reduces haematocrit and thrombosis risk?

Accepted Answer

Venesection (phlebotomy)

Answer

Hydroxyurea

Answer

Low-dose aspirin alone

Answer

Interferon-alpha

Answer

Ruxolitinib

Practice question

A 60-year-old male with polycythaemia vera has itching after hot baths, headaches, and elevated haematocrit with a JAK2 mutation. Which first-line treatment reduces haematocrit and thrombosis risk?