A 55-year-old man with chronic myeloid leukaemia is being treated with imatinib. Which abnormality is most characteristic of CML on a cellular level?...

Question

A 55-year-old man with chronic myeloid leukaemia is being treated with imatinib. Which abnormality is most characteristic of CML on a cellular level?

Accepted Answer

BCR-ABL fusion gene (Philadelphia chromosome)

Answer

t(15;17) translocation

Answer

JAK2 mutation

Answer

RAS mutation

Answer

p53 mutation

ukmla MCQ (SBA): Chronic myeloid leukaemia