Question

A 45-year-old woman has weight gain, purple striae, proximal muscle weakness, and no cortisol suppression on overnight dexamethasone test, but partial suppression on high-dose test. What is the likely source of hypercortisolism?

Accepted Answer

Pituitary adenoma (Cushing's disease)

Answer

Adrenal adenoma

Answer

Ectopic ACTH (small cell lung cancer)

Answer

Exogenous steroid use

Answer

Phaeochromocytoma

Practice question

A 45-year-old woman has weight gain, purple striae, proximal muscle weakness, and no cortisol suppression on overnight dexamethasone test, but partial suppression on high-dose test. What is the likely source of hypercortisolism?