A 30-year-old patient presents with low mood, anhedonia, and reduced energy for 6 weeks, with no psychotic features. According to NICE, what is the fi...

Question

A 30-year-old patient presents with low mood, anhedonia, and reduced energy for 6 weeks, with no psychotic features. According to NICE, what is the first-line pharmacological treatment for moderate to severe depression?

Accepted Answer

Selective serotonin reuptake inhibitor (e.g. sertraline)

Answer

Tricyclic antidepressant (e.g. amitriptyline)

Answer

Monoamine oxidase inhibitor (e.g. phenelzine)

Answer

Atypical antipsychotic

Answer

Psychostimulants

NICE Depression Guideline MCQ (SBA): Depression

A 30-year-old patient presents with low mood, anhedonia, and reduced energy for 6 weeks, with no psychotic features. According to NICE, what is the first-line pharmacological treatment for moderate to severe depression?