Question

A 40-year-old patient with obesity hypertension and purple striae is suspected of having Cushing's syndrome. Initial low-dose dexamethasone suppression test shows lack of cortisol suppression. According to NICE guidelines what is the most appropriate next step?

Accepted Answer

Plasma ACTH measurement

Answer

High-dose dexamethasone suppression test

Answer

Immediate pituitary surgery

Answer

Metyrapone therapy

Answer

Adrenal CT scan

Practice question

A 40-year-old patient with obesity hypertension and purple striae is suspected of having Cushing's syndrome. Initial low-dose dexamethasone suppression test shows lack of cortisol suppression. According to NICE guidelines what is the most appropriate next step?