Question

A 42-year-old with longstanding depression has been on SSRI therapy for 8 weeks with minimal improvement. He denies suicidality. Which is the next best step?

Accepted Answer

Assess adherence and consider increasing SSRI dose or continue for up to 12 weeks

Answer

Switch to electroconvulsive therapy

Answer

Augment with an antipsychotic immediately

Answer

Stop SSRI and switch to TCA

Answer

Immediate referral for inpatient care

Practice question

A 42-year-old with longstanding depression has been on SSRI therapy for 8 weeks with minimal improvement. He denies suicidality. Which is the next best step?