Question

A 55-year-old man complains of heartburn and regurgitation especially at night. He has tried lifestyle modifications without relief. What is the next best pharmacological therapy?

Accepted Answer

Proton pump inhibitor (PPI) once daily

Answer

Antacid suspensions alone

Answer

H2 receptor antagonist (e.g., ranitidine)

Answer

Prokinetic agent (e.g., metoclopramide)

Answer

Surgery (Nissen fundoplication)

Practice question

A 55-year-old man complains of heartburn and regurgitation especially at night. He has tried lifestyle modifications without relief. What is the next best pharmacological therapy?