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Knowledge Centre / Weight Loss (Unintentional)

Weight Loss (Unintentional)

Investigation of unexpected weight loss.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
General PracticeOncologyGastroenterology

Clinical Guidelines

Assessment of unintentional weight loss
National
CKS: Adult malnutrition
National
ESPEN guidelines on definitions and terminology of clinical nutrition
National
NICE guideline [NG12]: Suspected cancer: recognition and referral
National
NICE guideline [NG84]
National
Diagnostic criteria for malnutrition – An ESPEN Consensus Statement
Local
Diagnostic criteria for malnutrition–An ESPEN Consensus Statement
Local

Recent iatroX Q&As

  • What initial investigations should I consider for a patient presenting with unintentional weight loss?Updated: 8/16/2025
  • How do I differentiate between benign causes and serious underlying conditions in patients with unexplained weight loss?Updated: 8/16/2025
  • What red flag symptoms should prompt urgent referral for a patient with unintentional weight loss?Updated: 8/16/2025
  • How should I approach the management of a patient with unintentional weight loss and no obvious cause after initial assessment?Updated: 8/16/2025
  • What role do dietary assessments play in the evaluation of unintentional weight loss in primary care?Updated: 8/16/2025
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