Syphilis

Diagnosis and management.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Sexual HealthInfectious Diseases

Clinical Guidelines

2020 European guideline on the management of syphilis
National
BASHH Guidelines for the Management of Syphilis 2024
National
CKS: Management of Syphilis
National
CKS: Syphilis
National
UK National Guidelines on the Management of Syphilis 2015
National
WHO guidelines for the treatment of Treponema pallidum (syphilis)
National
2020 European guideline on the management of syphilis (IUSTI/European STI Guidelines Editorial Board)
Local
CDC Clinical Guidelines on the Use of Doxycycline Postexposure Prophylaxis for Bacterial Sexually Transmitted Infections
Local
Recommendations for Treatment of Syphilis - WHO STI Guidelines
Local
Recommendations on syphilis screening and treatment for pregnant women - WHO STI Guidelines
Local
Screening for Syphilis in Pregnancy | ACOG Practice Advisory
Local
Screening for Syphilis Infection in Pregnancy: US Preventive Services Task Force Recommendation Statement
Local
Syphilis - STI Treatment Guidelines (CDC 2021)
Local
Syphilis: Adult and Adolescent Opportunistic Infections Guidelines (NIH)
Local
Syphilis: Screening and diagnostic testing - Canadian Guidelines
Local
Syphilis: Treatment and follow-up - Canadian Guidelines
Local