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Knowledge Centre / Staphylococcal Scalded Skin Syndrome (SSSS)

Staphylococcal Scalded Skin Syndrome (SSSS)

Diagnosis and management of toxin-mediated skin blistering.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 30 August 2025
DermatologyInfectious DiseasesPaediatrics

Clinical Guidelines

Staphylococcal scalded skin syndrome – Primary Care Dermatology Society (PCDS) Clinical Guidance
National

Recent iatroX Q&As

  • What clinical features should I look for to differentiate Staphylococcal Scalded Skin Syndrome (SSSS) from other blistering skin conditions?Updated: 8/22/2025
  • How should I manage fluid and electrolyte balance in a patient with SSSS presenting with extensive skin involvement?Updated: 8/22/2025
  • When should I consider referring a patient with SSSS to a specialist for further management?Updated: 8/22/2025
  • What are the recommended antibiotic therapies for treating Staphylococcal Scalded Skin Syndrome in children?Updated: 8/22/2025
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