Sickle Cell Disease

Management and acute crises.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Haematology

Clinical Guidelines

CKS: Sickle cell disease
National
NICE guideline [CG143]
National
NICE guideline [CG143]: Sickle cell disease: managing acute painful episodes in hospital
National
American Society of Hematology 2019 guidelines for sickle cell disease: cardiopulmonary and kidney disease
Local
American Society of Hematology 2020 guidelines for sickle cell disease: management of acute and chronic pain
Local
American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support
Local
American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation
Local
An official American Thoracic Society clinical practice guideline: Diagnosis and management of pulmonary hypertension of sickle cell disease
Local
CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022
Local
Clinical Practice Guidelines on Sickle Cell Disease (ASH)
Local
Evidence-Based Management of Sickle Cell Disease: Expert Panel Report, 2014 (NHLBI/NIH)
Local
Society for Maternal-Fetal Medicine Consult Series #68: Sickle cell disease in pregnancy
Local
Standards for the Clinical Care of Adults with Sickle Cell Disease in the UK (Sickle Cell Society, 2018)
Local