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Knowledge Centre / Serotonin Syndrome

Serotonin Syndrome

Recognition and management of serotonergic toxicity.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
ToxicologyMental HealthEmergency Medicine

Clinical Guidelines

Clinical Practice Guidelines: Serotonin toxicity (Royal Children's Hospital Melbourne)
National
Guidelines for the management of serotonin syndrome (NHS Scotland Right Decisions)
National
IAEM Clinical Guideline - Serotonin Syndrome
National
Clinical Practice Guidelines : Serotonin toxicity
Local
Prevention, Diagnosis, and Management of Serotonin Syndrome
Local

Recent iatroX Q&As

  • How should I differentiate between serotonin syndrome and other similar conditions, such as neuroleptic malignant syndrome?Updated: 8/22/2025
  • When should I consider referring a patient with serotonin syndrome to secondary care?Updated: 8/22/2025
  • What are the potential drug interactions that could lead to serotonin syndrome that I should be aware of in my prescribing practices?Updated: 8/22/2025
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