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Knowledge Centre / Pruritus (Itching)

Pruritus (Itching)

Assessment and management of generalized itching.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
DermatologyGeneral Practice

Clinical Guidelines

CKS: Itch - widespread
National
ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
Local
ACOG Practice Bulletin, Number 215: Vaginitis in Nonpregnant Patients
Local
ACOG Practice Bulletin, Number 224: Diagnosis and Management of Vulvar Skin Disorders
Local
EASL Clinical Practice Guidelines: The diagnosis and management of primary biliary cholangitis
Local
MASCC Clinical Practice Guidelines for the Prevention and Management of Acute Radiation Dermatitis
Local
Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases
Local

Recent iatroX Q&As

  • What are the key differential diagnoses to consider in a patient presenting with generalized pruritus?Updated: 8/22/2025
  • What topical treatments are recommended for managing pruritus in patients with eczema or dermatitis?Updated: 8/22/2025
  • When should I consider referring a patient with generalized itching to a dermatologist?Updated: 8/22/2025
  • What role do systemic conditions play in generalized pruritus, and how should they be assessed in primary care?Updated: 8/22/2025
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