Neuroleptic Malignant Syndrome (NMS)

Recognition and management of antipsychotic drug reaction.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Mental HealthEmergency MedicineCritical Care

Clinical Guidelines

CKS: Bipolar Disorder - Antipsychotics
National
CKS: Psychosis and Schizophrenia - Adverse Effects
National
Evidence-based consensus guidelines for the management of catatonia and neuroleptic malignant syndrome
Local
Royal College of Psychiatrists Consensus Statement on High-Dose Antipsychotic Medication (CR190)
Local