Leg Cramps

Management of nocturnal leg cramps.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
General Practice

Clinical Guidelines

CKS: Leg cramps
National
NICE CKS: Leg cramps
National
NICE CKS: Management of leg cramps
National
Quinine: not to be used routinely for nocturnal leg cramps
National
Assessment: Symptomatic treatment for muscle cramps (an evidence-based review): Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Local
Leg cramps | Health topics A to Z | CKS | NICE
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Quinine for Leg Cramps | AAFP
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Quinine: not to be used routinely for nocturnal leg cramps - GOV.UK
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