Hypersensitivity Reactions

Overview of Gell and Coombs classification of immune reactions.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
ImmunologyAllergy

Clinical Guidelines

CKS: Angio-oedema and anaphylaxis
National
NICE guideline [CG183]: Drug allergy: diagnosis and management
National
CAR/CSACI Practice Guidance for Contrast Media Hypersensitivity
Local
Drug allergy: A 2022 practice parameter update
Local
Expert Consensus Statement from the American Society of Echocardiography on Hypersensitivity Reactions to Ultrasound Enhancing Agents in Patients with Allergy
Local
General Best Practice Guidelines for Immunization
Local
Hypersensitivity reactions to contrast media: Part 1. Management of immediate and non-immediate hypersensitivity reactions in adults. Updated guidelines by the ESUR Contrast Media Safety Committee
Local
ISPAD Clinical Practice Consensus Guidelines 2022: Diabetes technologies: Glucose monitoring
Local
Management and Prevention of Hypersensitivity Reactions to Radiocontrast Media: A Consensus Statement
Local
Management and Prevention of Hypersensitivity Reactions to Radiocontrast Media: A Consensus Statement From the American College of Radiology and the American Academy of Allergy, Asthma & Immunology
Local
Management and Prevention of Hypersensitivity Reactions to Radiocontrast Media: A Consensus Statement from the Radiological Society of North America (RSNA)
Local
Management of infusion reactions to systemic anticancer therapy: ESMO Clinical Practice Guidelines
Local
Management of infusion-related reactions in cancer therapy: ESMO Clinical Practice Guidelines
Local