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Knowledge Centre / Herpes Simplex Virus (HSV)

Herpes Simplex Virus (HSV)

Overview of HSV-1 and HSV-2 infections (oral, genital, systemic).

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Infectious DiseasesSexual HealthDermatology

Clinical Guidelines

CKS: Herpes simplex - genital
National
CKS: Herpes simplex - ocular
National
CKS: Herpes simplex - oral
National
Management of Genital Herpes in Pregnancy | RCOG
National
WHO guidelines for the treatment of Genital Herpes Simplex Virus
National
Herpes simplex keratitis (HSK) - College of Optometrists Clinical Management Guideline
Local
Herpes Simplex Virus: Adult and Adolescent OIs | NIH
Local
Joint British Association for Sexual Health and HIV and Royal College of Obstetricians and Gynaecologists guideline on the management of herpes simplex virus (HSV) in pregnancy and the neonate (2024 update)
Local
Management of Genital Herpes in Pregnancy | RCOG
Local
Management of Genital Herpes in Pregnancy: ACOG Practice Bulletin, Number 220
Local
Management of Genital Herpes in Pregnancy: ACOG Practice Bulletin, Number 220
Local
Recommendation: Genital Herpes Infection: Serologic Screening | US Preventive Services Task Force
Local
Sexually Transmitted Infections Treatment Guidelines, 2021 | CDC
Local

Recent iatroX Q&As

  • What are the key clinical features that help differentiate between oral HSV-1 and genital HSV-2 infections in primary care?Updated: 8/22/2025
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