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Knowledge Centre / First Seizure

First Seizure

Assessment and management of a suspected first seizure.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
NeurologyEmergency Medicine

Clinical Guidelines

CKS: Epilepsy - Suspected epilepsy
National
NICE guideline [CG137]
National
NICE guideline [NG217]
National
NICE guideline [NG217]: Epilepsies in children, young people and adults
National
SIGN 143 • Diagnosis and management of epilepsy in adults
National
Epilepsies: diagnosis and management (NICE Guideline CG137)
Local
Evidence-based guideline: Management of an unprovoked first seizure in adults (2015; reaffirmed 2024)
Local
Evidence-based guideline: Management of an unprovoked first seizure in adults (AAN/AES)
Local
Management of an Unprovoked First Seizure in Adults (AAN Guideline)
Local

Recent iatroX Q&As

  • What initial assessments should I perform for a patient presenting with a suspected first seizure?Updated: 8/16/2025
  • How do I differentiate between a seizure and other conditions that may mimic seizure activity in primary care?Updated: 8/16/2025
  • What are the guidelines for referring a patient for further investigation after a first seizure?Updated: 8/16/2025
  • What follow-up care should I provide for a patient after their first seizure, including lifestyle advice and monitoring?Updated: 8/16/2025
  • When should I consider starting antiepileptic medication in a patient who has had a first seizure?Updated: 8/16/2025
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