Chronic Fatigue Syndrome (ME/CFS)

Diagnosis and management of ME/CFS.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
General PracticeNeurology

Clinical Guidelines

Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management
National
CKS: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
National
NICE guideline [NG206]
National
NICE guideline [NG206]: Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management
National
Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness (Institute of Medicine Report 2015)
Local
NICE guideline [NG206]: Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome (ME/CFS): diagnosis and management
Local
US ME/CFS Clinician Coalition Consensus Statement: Diagnosing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Patients with Post-COVID Conditions
Local