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Knowledge Centre / Acanthosis Nigricans

Acanthosis Nigricans

Management of skin darkening associated with insulin resistance.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
DermatologyEndocrinology

Clinical Guidelines

PCDS Clinical Guidance: Acanthosis nigricans
National
2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2024
Local
ACOG Practice Bulletin No. 190: Gestational Diabetes Mellitus
Local
ACOG Practice Bulletin No. 194: Polycystic Ovary Syndrome
Local
Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity
Local
ISPAD Clinical Practice Consensus Guidelines 2018: Definition, epidemiology, and classification of diabetes in children and adolescents
Local
ISPAD Clinical Practice Consensus Guidelines 2018: Stages of type 1 diabetes in children and adolescents
Local
ISPAD Clinical Practice Consensus Guidelines 2018: The diagnosis and management of monogenic diabetes in children and adolescents
Local
ISPAD Clinical Practice Consensus Guidelines 2024: Type 2 Diabetes in Children and Adolescents
Local

Recent iatroX Q&As

  • How should I investigate a patient with acanthosis nigricans to assess for underlying insulin resistance or metabolic syndrome?Updated: 8/22/2025
  • What lifestyle modifications should I recommend to a patient with acanthosis nigricans to improve their insulin sensitivity?Updated: 8/22/2025
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