Lexicomp vs RxFiles (2025): The Database vs The Charts

Last reviewed: 2025-12-19 · Reviewed by

At a Glance

Who is it for?

Lexicomp:Clinicians

RxFiles:Visual Learners

Why choose Lexicomp?

  • **Search**: Instant retrieval of specific facts.
  • **Safety**: Deep interaction and allergy checking.
  • **Updates**: Real-time updates.

Why choose RxFiles?

  • **Comparison**: Displays an entire drug class on one page.
  • **Nuance**: Highlights trial data and NNT (Number Needed to Treat).
  • **Switching**: Excellent guides for converting between drugs.

Feature Comparison

CapabilityLexicompRxFiles
FormatDigital / TextPDF / Grid
GoalVerificationSelection

In-Depth Analysis

Overview

Lexicomp is a reference tool; it gives you the facts. RxFiles is a decision tool; it gives you the comparison. Use RxFiles to choose the drug, and Lexicomp to prescribe it.

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Use-Cases

Selecting the best SSRI

When to choose Lexicomp

  • Hard to compare side-by-side.

When to choose RxFiles

  • **Winner.** Excellent comparison table.

Checking Liver Toxicity

When to choose Lexicomp

  • **Winner.** Detailed monograph.

When to choose RxFiles

  • Limited space for detail.