AMH vs Lexicomp (2025): National Handbook vs Global Database

Last reviewed: 2025-12-19 · Reviewed by

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At a Glance

Who is it for?

AMH:Australian Clinicians

Lexicomp:Pharmacists / Hospitals

Why choose AMH?

  • **Relevance**: Only lists drugs available in Australia.
  • **Concise**: Edited for quick reading.
  • **Guidelines**: Aligned with Australian Therapeutic Guidelines.

Why choose Lexicomp?

  • **Depth**: Much deeper pharmacology and safety data.
  • **Interactions**: World-leading interaction checker.
  • **Off-Label**: Extensive coverage of non-approved uses.

Feature Comparison

CapabilityAMHLexicomp
ScopeAustraliaInternational / US
DetailEssentialExhaustive

In-Depth Analysis

Overview

AMH is the book you carry in your pocket (or keep on your phone) for 99% of tasks in Australia. Lexicomp is the heavy-duty tool you log into when you have a complex patient on 15 medications and need to check for subtle interactions.

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Use-Cases

Routine Prescribing

When to choose AMH

  • **Winner.** Faster and locally relevant.

When to choose Lexicomp

  • Can be too detailed (US brand names).

Complex Interaction Check

When to choose AMH

  • Good.

When to choose Lexicomp

  • **Winner.** The specialist standard.